Rather than simply going with my gut reaction to the prospect of not being able to backwind, I actually bought a
Stradic Ci4+ FB to see for myself. It's a belting little reel and I certainly did manage perfectly well with it. However, after a fair bit of use, and despite me not being a regular backwinder, I came to the conclusion that I'd simply prefer to have the anti-reverse switch than not. I found that I was instinctively reaching for the switch at times. Force of habit over many years has obviously left its mark. I've also never needed a reel to have superior waterproofing, I don't dunk reels in venues and I don't fish in saltwater environments.
Dedicated backwinders are obviously never going to get on with such a reel. They'd be daft to even try to. However, I suspect that many of those that tend to actually use the drags on their reels will have few problems adapting, provided they actually want to.